Research programme: sphingosine-1 phosphate receptor agonists - AbbVie

Drug Profile

Research programme: sphingosine-1 phosphate receptor agonists - AbbVie

Alternative Names: ABT-363; S1P5 - AbbVie; Sphingosine-1 phosphate receptor 5 agonists - AbbVie

Latest Information Update: 22 Jun 2018

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At a glance

  • Originator Abbott Laboratories
  • Developer AbbVie
  • Class Small molecules
  • Mechanism of Action Sphingosine 1 phosphate receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Lysosomal-storage diseases

Most Recent Events

  • 18 Jun 2018 E-Scape Bio in-licenses selective S 1P 5 receptor agonists AbbVie
  • 18 Jun 2018 Sphingosine-1 phosphate receptor agonists are still in preclinical trials for lysosomal storage disorders in the US
  • 12 Jun 2018 E-Scape Bio announces intention to submit IND-application to the US FDA for lysosomal storage disorders in 2019
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