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Lotamilast - Dermavant Sciences

Drug Profile

Lotamilast - Dermavant Sciences

Alternative Names: DMVT 501; E 6005; RVT-501

Latest Information Update: 04 Nov 2018

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At a glance

  • Originator Eisai Co Ltd
  • Developer Dermavant Sciences; Eisai Co Ltd
  • Class Benzoates; Quinazolines; Skin disorder therapies
  • Mechanism of Action Type 4 cyclic nucleotide phosphodiesterase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Atopic dermatitis

Most Recent Events

  • 02 Jul 2018 Dermavant Sciences completes a phase II trial in Atopic dermatitis (In adolescents, In children) in Canada, USA (Topical) (NCT03394677)
  • 24 Jun 2018 Biomarkers information updated
  • 31 Jan 2018 Phase-I clinical trials in Atopic dermatitis (In children) in USA (Topical) (NCT03415282)
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