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MEDI 6469

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Drug Profile

MEDI 6469

Alternative Names: Anti-OX40 monoclonal antibody; MEDI-6469; Murine-anti-OX40-MAb

Latest Information Update: 12 Feb 2024

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At a glance

  • Originator AgonOx; Providence Cancer Center
  • Developer AstraZeneca; Providence Cancer Center
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Immunomodulators; OX40 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Breast cancer; Colorectal cancer; Diffuse large B cell lymphoma; Head and neck cancer; Prostate cancer; Solid tumours

Most Recent Events

  • 21 Dec 2023 Providence Cancer Center completes phase I trials in Head and neck cancer (First-line therapy, Neoadjuvant therapy, Late-stage disease) in USA (IV) (NCT02274155)
  • 14 Feb 2022 Providence Health Services and MedImmune terminates a phase I/II trial in Colorectal cancer (Metastatic disease) in USA (IV) (NCT02559024)
  • 28 Oct 2018 No recent reports of development identified for phase-I development in Colorectal-cancer(Metastatic disease) in USA (IV, Infusion)

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