Drug Profile
MEDI 6469
Alternative Names: Anti-OX40 monoclonal antibody; MEDI-6469; Murine-anti-OX40-MAbLatest Information Update: 12 Feb 2024
Price :
$50
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At a glance
- Originator AgonOx; Providence Cancer Center
- Developer AstraZeneca; Providence Cancer Center
- Class Antineoplastics; Monoclonal antibodies
- Mechanism of Action Immunomodulators; OX40 receptor agonists
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Discontinued Breast cancer; Colorectal cancer; Diffuse large B cell lymphoma; Head and neck cancer; Prostate cancer; Solid tumours
Most Recent Events
- 21 Dec 2023 Providence Cancer Center completes phase I trials in Head and neck cancer (First-line therapy, Neoadjuvant therapy, Late-stage disease) in USA (IV) (NCT02274155)
- 14 Feb 2022 Providence Health Services and MedImmune terminates a phase I/II trial in Colorectal cancer (Metastatic disease) in USA (IV) (NCT02559024)
- 28 Oct 2018 No recent reports of development identified for phase-I development in Colorectal-cancer(Metastatic disease) in USA (IV, Infusion)