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Sacubitril

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Drug Profile

Sacubitril

Alternative Names: AHU-377

Latest Information Update: 23 Dec 2021

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At a glance

  • Originator Novartis
  • Class Antihypertensives; Biphenyl compounds; Esters; Pentanoic acids; Small molecules
  • Mechanism of Action Neprilysin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Essential hypertension

Most Recent Events

  • 31 Dec 2011 Novartis completes a phase II trial in Essential hypertension in USA, Argentina, Canada, Hungary, Romania, Slovakia, Spain, South Korea & India (NCT01281306)
  • 17 Oct 2011 Phase-II clinical trials in Essential hypertension in Argentina (PO)
  • 17 Oct 2011 Phase-II clinical trials in Essential hypertension in India (PO)

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