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Trotabresib - Celgene Corporation

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Drug Profile

Trotabresib - Celgene Corporation

Alternative Names: BET inhibitor - Celgene Corporation; BMS-986378; CC 90010; QC5487; TROTA - Celgene Corporation

Latest Information Update: 28 Jan 2025

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At a glance

  • Originator Quanticel Pharmaceuticals
  • Developer Bristol-Myers Squibb; Celgene Corporation
  • Class Antineoplastics; Isoquinolines; Ketones; Small molecules
  • Mechanism of Action Bromodomain and extraterminal domain protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Solid tumours
  • Phase I/II Glioblastoma
  • No development reported Astrocytoma; Non-Hodgkin's lymphoma

Most Recent Events

  • 28 Jan 2025 No recent reports of development identified for phase-I development in Astrocytoma(Late-stage disease, Recurrent, Second-line therapy or greater, Neoadjuvant therapy) in Spain (PO)
  • 28 Jan 2025 No recent reports of development identified for phase-I development in Astrocytoma(Late-stage disease, Recurrent, Second-line therapy or greater, Neoadjuvant therapy) in USA (PO)
  • 28 Jan 2025 No recent reports of development identified for phase-I development in Glioblastoma(Late-stage disease, Recurrent, Second-line therapy or greater, Neoadjuvant therapy) in Spain (PO)

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