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Nemiralisib - GlaxoSmithKline

Drug Profile

Nemiralisib - GlaxoSmithKline

Alternative Names: [14C]-GSK2269557; GSK 2269557; GSK 2269557 ELLIPTA DPI

Latest Information Update: 28 Nov 2019

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At a glance

  • Originator GlaxoSmithKline
  • Class Antiasthmatics; Indazoles; Indoles; Oxazoles; Piperazines; Small molecules
  • Mechanism of Action Phosphatidylinositol 3 kinase delta inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Asthma; Chronic obstructive pulmonary disease; Immunodeficiency disorders
  • Phase I Bronchiectasis

Most Recent Events

  • 28 Nov 2019 No recent reports of development identified for phase-I development in Chronic-obstructive-pulmonary-disease(In volunteers) in Japan (Inhalation, Powder)
  • 10 Jan 2019 GlaxoSmithKline terminates phase II trial in Chronic obstructive pulmonary disease (In adults, In the elderly) in Argentina, Australia, Canada, France, Germany, Italy, Mexico, Netherlands, Poland, Romania, Russia, Scotland, South Korea, Spain, Sweden, United Kingdom, USA (EudraCT2017-001074-42) (NCT03345407)
  • 27 Jul 2018 GlaxoSmithKline initiates a phase IIa trial in Chronic obstructive pulmonary disease (In adults, In the elderly) in Spain (Inhalation) (EudraCT2017-004564-35)
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