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Seviteronel - Innocrin Pharmaceuticals

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Drug Profile

Seviteronel - Innocrin Pharmaceuticals

Alternative Names: INO-464; VT-464

Latest Information Update: 10 Jul 2026

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At a glance

  • Originator Viamet Pharmaceuticals
  • Developer Innocrin Pharmaceuticals
  • Class Antiandrogens; Antineoplastics; Fluorine compounds; Naphthalenes; Propanols; Small molecules; Triazoles
  • Mechanism of Action Androgen receptor antagonists; Estrogen receptor antagonists; Steroid 17-alpha-hydroxylase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Breast cancer; Prostate cancer; Solid tumours
  • Phase I/II Triple negative breast cancer

Most Recent Events

  • 22 Apr 2026 Adverse events and efficacy data from the phase Ib/II trial presented at the 117th Annual Meeting of the American Association for Cancer Research (AACR-2026)
  • 31 May 2024 Efficacy and adverse event data from the phase Ib/II 4CAST trial in Triple negative breast cancer presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)
  • 01 Jul 2022 Phase-I/II clinical trials in Triple-negative-breast-cancer (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater, Recurrent) in Australia (PO) (NCT04947189)

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