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Cipargamin - Novartis

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Drug Profile

Cipargamin - Novartis

Alternative Names: Cipargamin; KAE-609; KAW-609; NITD-609

Latest Information Update: 15 Mar 2024

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At a glance

  • Originator Novartis
  • Developer Medicines for Malaria Venture; Novartis; The Wellcome Trust
  • Class Antimalarials; Carbolines; Indoles; Pyridones; Small molecules; Spiro compounds
  • Mechanism of Action PfATP4 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Malaria
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Falciparum malaria; Malaria

Most Recent Events

  • 02 Mar 2024 Novartis Pharmaceuticals completes a phase I trial in Malaria (In volunteers, Combination therapy) in United Kingdom (PO) (ISRCTN17232240)
  • 23 Jan 2024 Phase-II clinical trials in Falciparum malaria (Combination therapy, In children, In adults, In adolescents, In the elderly) in Ivory Coast, Ghana, Kenya (PO) (NCT05750628)
  • 23 Jan 2024 Phase-II clinical trials in Falciparum malaria (In adolescents, In children, In adults, In the elderly, Monotherapy) in Kenya, Ghana, Ivory Coast (PO) (NCT05750628)

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