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Doravirine - Merck & Co

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Drug Profile

Doravirine - Merck & Co

Alternative Names: MK-1439; MK-1439-019; Pifeltro; PIFELTRO

Latest Information Update: 04 Dec 2025

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At a glance

  • Originator Merck & Co
  • Developer Merck & Co; National Institute of Allergy and Infectious Diseases
  • Class Antiretrovirals; Benzonitrile; Chlorinated hydrocarbons; Fluorinated hydrocarbons; Pyridones; Small molecules; Triazoles
  • Mechanism of Action Non-nucleoside reverse transcriptase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - HIV-1 infections
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed HIV-1 infections

Most Recent Events

  • 04 Dec 2025 Launched for HIV-1 infections (In the elderly, In children, In adults) in USA (PO), prior to December 2025 (Merck & Co website, December 2025)
  • 04 Dec 2025 Launched for HIV-1 infections in China (PO), prior to December 2025 (Merck & Co website, December 2025)
  • 04 Dec 2025 Launched for HIV-1 infections in Japan (PO), prior to December 2025 (Merck & Co website, December 2025)

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