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Doravirine - Merck & Co

Drug Profile

Doravirine - Merck & Co

Alternative Names: MK-1439; MK-1439-019; Pifeltro; PIFELTRO

Latest Information Update: 26 Apr 2023

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At a glance

  • Originator Merck & Co
  • Developer Merck & Co; National Institute of Allergy and Infectious Diseases
  • Class Antiretrovirals; Benzonitrile; Chlorinated hydrocarbons; Fluorinated hydrocarbons; Pyridones; Small molecules; Triazoles
  • Mechanism of Action Non-nucleoside reverse transcriptase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - HIV-1 infections
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed HIV-1 infections

Most Recent Events

  • 06 Mar 2023 Merck Sharp & Dohme LLC completed a phase III trial in HIV-1 infections (Combination therapy, Treatment-naive) in Austria, Denmark, Germany, Italy, Portugal, Romania, Spain, United Kingdom (PO) (NCT02275780) (EudraCT2014-001127-69)
  • 11 May 2022 Preregistration for HIV-1 infections (In children, In adults, In the elderly) in European Union (PO) (Merck pipeline, May 2022)
  • 11 May 2022 Preregistration for HIV-1 infections (In children, In adults, In the elderly) in USA (PO) (Merck pipeline, May 2022)
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