Research programme: GSG2 protein/CDK8 inhibitors - Selvita

Drug Profile

Research programme: GSG2 protein/CDK8 inhibitors - Selvita

Alternative Names: SEL 120; SEL120-34; SEL120-34A

Latest Information Update: 07 Feb 2018

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At a glance

  • Originator Selvita
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Cyclin-dependent kinase 8 inhibitors; GSG2 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Breast cancer; Colorectal cancer; Haematological malignancies; Solid tumours

Most Recent Events

  • 06 Apr 2018 Selvita plans a phase I trial of SEL 120 for Acute myeloid leukaemia in first quarter of 2019
  • 06 Feb 2018 Preclinical trials in Haematological malignancies in Poland (PO), prior to February 2018
  • 06 Feb 2018 Preclinical trials in Solid tumours in Poland (PO), prior to February 2018
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