Riboflavin topical - Avedro

Drug Profile

Riboflavin topical - Avedro

Alternative Names: KXL; KXL System®; ParaCel; Paracel 1; Paracel 2 R0185; Photrexa; Photrexa Viscous; Riboflavin 5’-phosphate in 20% dextran ophthalmic solution; Riboflavin 5’-phosphate ophthalmic solution; Riboflavin ophthalmic solution; Riboflavin ophthalmic solution/KXL system; VibeX; VibeX Rapid; VibeX Xtra

Latest Information Update: 16 Apr 2018

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At a glance

  • Originator Avedro
  • Class Antimigraines; Flavins; Small molecules; Vitamins
  • Mechanism of Action Photosensitisers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Corneal injuries; Keratoconus
  • New Molecular Entity No

Highest Development Phases

  • Marketed Corneal injuries; Keratoconus

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 30 Mar 2018 Avedro initiates enrolment in a phase III trial for Keratoconus in USA (NCT03442751)
  • 22 Feb 2018 Avedro plans a phase III trial for Keratoconus (NCT03442751)
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