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Riboflavin topical - Avedro

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Drug Profile

Riboflavin topical - Avedro

Alternative Names: Epi-on; Epioxa; Epioxa HD; Epioxa™; iLink™; KXL; KXL System®; ParaCel; Paracel 1; Paracel 2 R0185; Photrexa; Photrexa Viscous; Riboflavin 5’-phosphate in 20% dextran ophthalmic solution; Riboflavin 5’-phosphate ophthalmic solution; Riboflavin ophthalmic solution; Riboflavin ophthalmic solution/KXL system; VibeX; VibeX Rapid; VibeX Xtra

Latest Information Update: 28 Oct 2025

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At a glance

  • Originator Avedro
  • Class Antimigraines; Eye disorder therapies; Flavins; Small molecules; Vitamins
  • Mechanism of Action Photosensitisers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Corneal injuries; Keratoconus
  • New Molecular Entity No

Highest Development Phases

  • Marketed Corneal injuries; Keratoconus

Most Recent Events

  • 20 Oct 2025 Registered for Keratoconus (In adolescents, In adults) in USA (Ophthalmic, Solution)
  • 20 Oct 2025 Glaukos plans to launch Epioxa for Keratoconus (In adolescents, In adults) in USA (Ophthalmic, Solution) in the first quarter of 2026
  • 24 Feb 2025 US FDA assigns PDUFA action date of (20/10/2025) for Riboflavin topical for Keratoconus

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