VXM 01

Drug Profile

VXM 01

Alternative Names: VEGFR2 peptide vaccine - VAXIMM; VEGFR2 specific T cell vaccine - VAXIMM; VXM-01

Latest Information Update: 14 Jun 2018

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At a glance

  • Originator Merck KGaA
  • Developer VAXIMM
  • Class Cancer vaccines; DNA vaccines; Peptide vaccines
  • Mechanism of Action Angiogenesis inhibitors; Immunostimulants; Vascular endothelial growth factor receptor-2 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioma
  • New Molecular Entity No

Highest Development Phases

  • Phase I Colorectal cancer; Glioblastoma
  • No development reported Pancreatic cancer; Solid tumours

Most Recent Events

  • 01 Jun 2018 Safety, efficacy and pharmacodynamics data from phase I trial in Glioblastoma presented at 54th Annual Meeting of the American Society of Clinical Oncology (ASCO-2018) (NCT02718443)
  • 28 Dec 2017 No recent reports of development identified for phase-I development in Pancreatic-cancer(Combination therapy, Inoperable/Unresectable, Late-stage disease) in Germany (PO, Liquid)
  • 28 Dec 2017 No recent reports of development identified for preclinical development in Solid-tumours in Switzerland (PO, Liquid)
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