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Ulixacaltamide - Praxis Precision Medicine

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Drug Profile

Ulixacaltamide - Praxis Precision Medicine

Alternative Names: PRAX-944; Z 944

Latest Information Update: 09 Dec 2025

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At a glance

  • Originator Zalicus
  • Developer Praxis Precision Medicines; Taro Pharmaceuticals USA
  • Class Analgesics; Antiepileptic drugs; Benzamides; Piperidines; Small molecules
  • Mechanism of Action T-type calcium channel antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Essential tremor
  • Phase II Epilepsy
  • No development reported Pain

Most Recent Events

  • 04 Dec 2025 Praxis Precision Medicines completes its pre-NDA meeting with FDA for Essential tremor
  • 05 Nov 2025 Praxis Precision Medicines plans pre-NDA meeting with the FDA in the fourth quarter of 2025
  • 05 Nov 2025 Efficacy data from a phase III Essential3 trial for Essential tremor released by Praxis Precision Medicines

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