Acebilustat - Celtaxsys

Drug Profile

Acebilustat - Celtaxsys

Alternative Names: CTX-4430; EP-501

Latest Information Update: 10 Aug 2018

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At a glance

  • Originator Unknown
  • Developer Celtaxsys
  • Class Anti-inflammatories; Antiacnes; Antifibrotics; Antihypertensives; Skin disorder therapies; Small molecules
  • Mechanism of Action Leukotriene A4 hydrolase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cystic fibrosis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Cystic fibrosis
  • Phase I Bronchiectasis; Pulmonary hypertension; Skin disorders
  • Discontinued Acne vulgaris; Hidradenitis suppurativa; Rosacea

Most Recent Events

  • 06 Aug 2018 Discontinued - Phase-I for Hidradenitis suppurativa in USA (unspecified route) (Celtaxsys pipeline, August 2018)
  • 06 Aug 2018 Discontinued - Phase-II for Acne vulgaris in New Zealand, Australia (PO) (Celtaxsys pipeline, August 2018)
  • 06 Aug 2018 Discontinued - Preclinical for Acne vulgaris in USA (Topical) (Celtaxsys pipeline, August 2018)
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