ALG 1001

Drug Profile

ALG 1001

Alternative Names: ALG-1001; Integrin Peptide Therapy; Luminate

Latest Information Update: 29 Dec 2017

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At a glance

  • Originator Allegro Ophthalmics
  • Class Anti-inflammatories; Eye disorder therapies; Oligopeptides
  • Mechanism of Action Integrin alpha 5 beta 1 modulators; Integrin alpha2beta1 modulators; Integrin alphaVbeta3 modulators; Integrin alphaVbeta5 modulators; Protein tyrosine kinase inhibitors; Vascular endothelial growth factor A inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Diabetic macular oedema; Diabetic retinopathy; Retinal disorders; Wet age-related macular degeneration

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for phase-I development in Diabetic-macular-oedema in Mexico (Intravitreous, Injection)
  • 09 Aug 2017 Efficacy and adverse events data from the phase IIb DEL MAR trial in Diabetic macular oedema released by Allegro Opthalmics
  • 25 Jul 2017 Allegro Ophthalmics plans multiple phase III trials in USA
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