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Idasanutlin - Roche

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Drug Profile

Idasanutlin - Roche

Alternative Names: RG-7388; RO-5503781

Latest Information Update: 24 Jul 2024

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At a glance

  • Originator Roche
  • Developer Mayo Clinic; National Cancer Institute (USA); NHS Greater Glasgow and Clyde; Roche; University of Glasgow
  • Class Aminobenzoic acids; Antineoplastics; Halogenated hydrocarbons; Pyrrolidines; Small molecules
  • Mechanism of Action Proto-oncogene protein c-mdm2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Acute myeloid leukaemia; Breast cancer; Cancer; Diffuse large B cell lymphoma; Essential thrombocythaemia; Follicular lymphoma; Glioblastoma; Multiple myeloma; Neuroblastoma; Non-Hodgkin's lymphoma; Polycythaemia vera; Precursor cell lymphoblastic leukaemia-lymphoma; Prostate cancer; Rhabdoid tumour; Solid tumours

Most Recent Events

  • 24 Jul 2024 Discontinued - Phase-I/II clinical trials in Precursor cell lymphoblastic leukaemia-lymphoma (In adolescents, In children, In infants, In neonates, Second-line therapy or greater, In adults, Monotherapy) in USA, United Kingdom, Spain, Netherlands, France, Canada (PO) (NCT04029688)
  • 24 Jul 2024 Discontinued - Phase-I/II clinical trials in Solid tumours (Second-line therapy or greater, In adults, In children, In adolescents, In infants, In neonates, Combination therapy) in Netherlands, France, Spain, Canada, USA, United Kingdom (PO) (NCT04029688)
  • 24 Jul 2024 Discontinued - Phase-I/II for Acute myeloid leukaemia (In adults, Second-line therapy or greater, In adolescents, Monotherapy, In neonates, In infants, In children) in France, Spain, Netherlands, Canada, US and the United Kingdom (PO)
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