Patisiran - Alnylam Pharmaceuticals

Drug Profile

Patisiran - Alnylam Pharmaceuticals

Alternative Names: ALN-18328; ALN-TTR02; GENZ-438027; Onpattro; Patisiran sodium - Alnylam Pharmaceuticals; SAR-438037

Latest Information Update: 17 Oct 2018

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At a glance

  • Originator Alnylam Pharmaceuticals
  • Class Oligonucleotides; Small interfering RNA
  • Mechanism of Action Prealbumin expression inhibitors; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Amyloidosis; Amyloid polyneuropathy
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Amyloid polyneuropathy; Amyloidosis

Most Recent Events

  • 12 Oct 2018 Silence Therapeutics initiates litigation against Alnylam Pharmaceuticals over commercialisation of patisiran across Europe
  • 02 Oct 2018 Launched for Amyloidosis in Germany (IV)
  • 28 Sep 2018 Preregistration for Amyloid polyneuropathy in Japan (IV)
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