Vericiguat - Bayer HealthCare Pharmaceuticals/Merck & Co
Alternative Names: BAY 102; BAY-1021189; MK-1242; VERQUVOLatest Information Update: 28 Feb 2025
At a glance
- Originator Bayer HealthCare Pharmaceuticals
- Developer Bayer HealthCare Pharmaceuticals; Merck & Co
- Class Amines; Carbamates; Fluorobenzenes; Heart failure therapies; Pyrazoles; Pyridines; Pyrimidines; Small molecules; Vasodilators
- Mechanism of Action Guanylate cyclase stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Marketed Chronic heart failure
- Phase II Metabolic syndrome
- No development reported Coronary artery disease
Most Recent Events
- 05 Feb 2025 Merck Sharp & Dohme completes the Phase-III VICTOR trial in Chronic heart failure in Italy, Poland, Sweden, Sweden, Brazil, Argentina, Canada, Chile, China, Colombia, Czech Republic, Denmark, France, Greece, Guatemala, Hong Kong, Ireland, South Africa, South Korea, Israel, Germany, Malaysia, Mexico, New Zealand, Peru, Singapore, Taiwan, Turkey, Ukraine, United Kingdom, Russia (PO) (NCT05093933)
- 01 Oct 2024 Phase-II/III clinical trials in Chronic heart failure (In adolescents, In children, In infants, In neonates) in Mexico (PO) (NCT05714085)
- 29 Jul 2024 Bayer completes a phase IIb trial for Chronic heart failure in USA, Argentina, Hungary, Italy, Poland, Spain, Sweden (PO, Tablet) (NCT06195930)