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Vericiguat - Bayer HealthCare Pharmaceuticals/Merck & Co

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Drug Profile

Vericiguat - Bayer HealthCare Pharmaceuticals/Merck & Co

Alternative Names: BAY 102; BAY-1021189; MK-1242; VERQUVO

Latest Information Update: 28 May 2024

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At a glance

  • Originator Bayer HealthCare Pharmaceuticals
  • Developer Bayer HealthCare Pharmaceuticals; Merck & Co
  • Class Amines; Carbamates; Fluorobenzenes; Heart failure therapies; Pyrazoles; Pyridines; Pyrimidines; Small molecules; Vasodilators
  • Mechanism of Action Guanylate cyclase stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Chronic heart failure
  • Phase II Metabolic syndrome
  • No development reported Coronary artery disease

Most Recent Events

  • 20 May 2024 Merck Sharp & Dohme plans a MK-1242-043 phase III trial for Chronic heart failure (In children, In adolescents, In adults, In the elderly) (PO) (NCT06428383)
  • 18 Apr 2024 Bayer initiates enrolment in a phase-II trial for Chronic heart failure in Argentina and USA (PO) (NCT06195930)
  • 06 Apr 2024 Updated efficacy data from a phase III VICTORIA trial presented at the 73rd Annual Scientific Session of the American College of Cardiology (ACC-2024)
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