KD 025

Drug Profile

KD 025

Alternative Names: KD-025; SLX-2119

Latest Information Update: 13 Mar 2018

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At a glance

  • Originator Surface Logix
  • Developer Kadmon Pharmaceuticals
  • Class Antifibrotics; Antineoplastics; Antipsoriatics; Antirheumatics; Small molecules
  • Mechanism of Action Rho-associated kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Graft-versus-host disease
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Graft-versus-host disease; Idiopathic pulmonary fibrosis; Plaque psoriasis
  • Phase I Scleroderma
  • Discontinued Autoimmune disorders; Non-alcoholic steatohepatitis; Rheumatoid arthritis; Systemic lupus erythematosus

Most Recent Events

  • 07 Mar 2018 Discontinued - Phase-I for Systemic lupus erythematosus in USA (PO)
  • 06 Mar 2018 Kadmon Corporation plans three phase II trials in Graft-versus-host disease, Idiopathic pulmonary fibrosis and Scleroderma
  • 12 Feb 2018 Adverse events and efficacy data from a phase II trial in Idiopathic pulmonary fibrosis released by Kadmon Pharmaceuticals
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