Drug Profile

BNC 101

Alternative Names: BNC-101; ET-101

Latest Information Update: 30 Dec 2024

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At a glance

Originator Biogen Idec
Developer Bionomics; Carina Biotech
Class Antineoplastics; Monoclonal antibodies
Mechanism of Action LGR5 protein inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Discontinued Cancer; Colorectal cancer; Solid tumours

Most Recent Events

23 Dec 2024 Bionomics re-domiciled from Australia to USA and became wholly owned subsidiary of Neuphoria Therapeutics
02 Aug 2022 Discontinued - Phase-I for Colorectal cancer (Combination therapy, Metastatic disease, Second-line therapy or greater) in Australia (IV)
02 Aug 2022 Discontinued - Phase-I for Colorectal cancer (Metastatic disease, Monotherapy, Second-line therapy or greater) in Australia (IV)

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