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Brilaroxazine - Reviva Pharmaceuticals

Drug Profile

Brilaroxazine - Reviva Pharmaceuticals

Alternative Names: RP 5000; RP-5063

Latest Information Update: 28 Sep 2022

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At a glance

  • Originator Reviva Pharmaceuticals
  • Class Antidepressants; Antifibrotics; Antipsychotics; Behavioural disorder therapies; Benzoxazines; Chlorobenzenes; Ethers; Ketones; Mood stabilisers; Piperazines; Small molecules
  • Mechanism of Action Dopamine D2 receptor partial agonists; Dopamine D3 receptor partial agonists; Dopamine D4 receptor partial agonists; Serotonin 1A receptor partial agonists; Serotonin 2A receptor partial agonists; Serotonin 6 receptor antagonists; Serotonin 7 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pulmonary arterial hypertension; Idiopathic pulmonary fibrosis
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Schizophrenia
  • Phase II Schizoaffective disorder
  • Phase I Idiopathic pulmonary fibrosis; Pulmonary arterial hypertension
  • No development reported Attention-deficit hyperactivity disorder; Bipolar disorders; Major depressive disorder; Psychotic disorders
  • Discontinued Autistic disorder; Gilles de la Tourette's syndrome

Most Recent Events

  • 28 Sep 2022 No recent reports of development identified for phase-I development in Attention-deficit-hyperactivity-disorder in USA (PO)
  • 28 Sep 2022 No recent reports of development identified for phase-I development in Bipolar-disorders in USA (PO)
  • 28 Sep 2022 No recent reports of development identified for phase-I development in Major depressive disorder in USA (PO)
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