Gepotidacin - GSK
Alternative Names: Blujepa; GSK 2140944; GSK-2140944ELatest Information Update: 10 Oct 2025
At a glance
- Originator GSK
- Class Acenaphthenes; Anti-infectives; Antibacterials; Aza compounds; Ketones; Piperidines; Pyridines; Pyrones; Small molecules; Urinary anti-infective agents
- Mechanism of Action DNA gyrase inhibitors; DNA topoisomerase IV inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Registered Urinary tract infections
- Phase III Gonorrhoea
- Discontinued Respiratory tract infections; Skin and soft tissue infections
Most Recent Events
- 11 Apr 2025 Antimicrobial data from preclinical trial in Urinary tract infections presented at the 35th Congress of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID-2025)
- 11 Apr 2025 Pharmacodynamics data from a preclinical trial in Urinary tract infection presented at the 35th Congress of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID-2025)
- 11 Apr 2025 Efficacy and adverse events data from phase-III EAGLE-J trial in Urinary tract infections presented at the 35th Congress of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID-2025)