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RG 2833

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Drug Profile

RG 2833

Alternative Names: RG-FA; RG2833; RGFP-109

Latest Information Update: 28 May 2025

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At a glance

  • Originator The Scripps Research Institute
  • Developer Johns Hopkins University; Repligen Corporation
  • Class Antineoplastics; Small molecules
  • Mechanism of Action HDAC1 protein inhibitors; HDAC3 protein inhibitors; Transcription factor stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Friedreich's ataxia
  • New Molecular Entity Yes
  • Available For Licensing Yes - Friedreich's ataxia

Highest Development Phases

  • No development reported Diffuse intrinsic pontine glioma; Friedreich's ataxia

Most Recent Events

  • 28 May 2025 No recent reports of development identified for preclinical development in Diffuse intrinsic pontine glioma in USA
  • 11 Apr 2021 Pharmacodynamics data from preclinical trials in Diffuse intrinsic pontine glioma presented at the 112th Annual Meeting of the American Association for Cancer Research (AACR-2021)
  • 10 Apr 2021 Preclinical trials in Diffuse intrinsic pontine glioma in USA (unspecified route), before April 2021

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