Drug Profile

Paxalisib - Kazia Therapeutics

Alternative Names: G-02441729; GDC-0084; RG 7666; SIM-0395; SVG-103

Latest Information Update: 03 Sep 2026

Price :

$50 ^*

Note:

Adis is an information provider. We do not sell or distribute actual drugs.
Final gross price and currency may vary according to local VAT and billing address.
Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

Originator Genentech
Developer Alliance for Clinical Trials in Oncology; Dana-Farber Cancer Institute; Genentech; Global Coalition for Adaptive Research; Huntsman Cancer Institute; John Hopkins University; Kazia Therapeutics; Memorial Sloan-Kettering Cancer Center; National Cancer Institute (USA); SoVarGen; St. Jude Childrens Research Hospital; University of California; Weill Cornell Medical College
Class Amines; Antineoplastics; Morpholines; Oxazines; Purines; Pyrimidines; Small molecules
Mechanism of Action 1 Phosphatidylinositol 3 kinase inhibitors; MTOR protein inhibitors; Proto-oncogene protein c-akt inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

Yes - Rhabdoid tumour; Diffuse intrinsic pontine glioma; Glioblastoma
New Molecular Entity Yes

Phase II/III Glioblastoma
Phase II Brain metastases; Glioma; Lymphoma
Phase I/II Cancer; Focal cortical dysplasia; Hemimegalencephaly; Tuberous sclerosis
Phase I Triple negative breast cancer
Preclinical Colorectal cancer; Malignant melanoma
No development reported Diffuse intrinsic pontine glioma; Meningeal carcinomatosis; Rhabdoid tumour

01 Sep 2026 Preclinical trials in Colorectal cancer in USA (PO)
01 Sep 2026 Pharmacodynamics data from a Preclinical trials in Colorectal cancer released by Kazia Therapeutics
01 Sep 2026 Kazia Therapeutics plans a phase II trial for colorectal cancer (Monotherapy, Combination therapy, metastatic disease) in the first quarter of 2027

If your organization or you do not have a subscription, try one of the following:

Contacting your organization’s admin about adding this content to your AdisInsight subscription
Buying a PDF version of any individual profile
Request a free trial (opens in a new window)

If your organization has a subscription, there are several access options, even while working remotely:

Working within your organization’s network
Login with username/password or try to access via your institution
Persisted access using your organization’s identifier stored in your user browser for 90 days

For assistance, contact us at asktheexpert.adisinsight@springer.com