Pegarginase - Bio-Cancer Treatment International

Drug Profile

Pegarginase - Bio-Cancer Treatment International

Alternative Names: BCT-100; PEG-arginase - Bio-Cancer Treatment International; PEG-BCT-100; PEGylated recombinant human arginase - Bio-Cancer Treatment International; Recombinant human arginase 1 - Bio-Cancer Treatment International; Recombinant human arginase I - Bio-Cancer Treatment International; rhArg1 - Bio-Cancer Treatment International; rhArgI - Bio-Cancer Treatment International; rhArgIpeg5000

Latest Information Update: 28 Dec 2017

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At a glance

  • Originator Bio-Cancer Treatment International
  • Class Antineoplastics; Polyethylene glycols; Ureohydrolases
  • Mechanism of Action Arginase replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Acute myeloid leukaemia; Hepatocellular carcinoma
  • Suspended Leukaemia; Lymphoma
  • No development reported Solid tumours

Most Recent Events

  • 06 Mar 2018 University of Birmingham plans the phase I/II PARC trial for Cancer (Late-stage disease, Second-line therapy or greater) (IV, Infusion) (NCT03455140)
  • 28 Dec 2017 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease, Second-line therapy or greater) in USA (IV, Infusion)
  • 27 Jul 2017 Bio-Cancer Treatment International Limited terminates a phase II trial for futility in Hepatocellular carcinoma (Monotherapy, Late-stage disease, Second-line therapy or greater, Inoperable/Unresectable) in Hong Kong (IV) (NCT02089763)
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