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Centanafadine - Otsuka Pharmaceutical

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Drug Profile

Centanafadine - Otsuka Pharmaceutical

Alternative Names: Centanafadine SR; Centanafadine XR; CTN SR; EB-1020; EB-1020 SR

Latest Information Update: 02 Dec 2025

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At a glance

  • Originator Euthymics Bioscience; Otsuka Pharmaceutical
  • Class Analgesics; Antidepressants; Azabicyclo compounds; Behavioural disorder therapies; Cyclohexanes; Naphthalenes; Small molecules; Smoking cessation therapies
  • Mechanism of Action Adrenergic uptake inhibitors; Dopamine uptake inhibitors; Serotonin uptake inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preregistration Attention-deficit hyperactivity disorder
  • Phase II Major depressive disorder; Smoking withdrawal
  • Discontinued Binge-eating disorder; Neuropathic pain

Most Recent Events

  • 25 Nov 2025 Preregistration for Attention-deficit hyperactivity disorder (In adolescents) in USA (PO)
  • 25 Nov 2025 Preregistration for Attention-deficit hyperactivity disorder (In adults) in USA (PO)
  • 25 Nov 2025 Preregistration for Attention-deficit hyperactivity disorder (In children) in USA (PO)

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