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Sunobinop - Imbrium Therapeutics/Shionogi

Drug Profile

Sunobinop - Imbrium Therapeutics/Shionogi

Alternative Names: IMB-115; IMB-115 tosylate; IT-1315; RSC117957; S-117957; Sunobinop tosylate; V-117957

Latest Information Update: 15 Mar 2022

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At a glance

  • Originator Purdue Pharma; Shionogi
  • Developer Imbrium Therapeutics; Purdue Pharma; Shionogi
  • Class Analgesics; Aza compounds; Carboxylic acids; Quinoxalines; Sleep disorder therapies; Small molecules
  • Mechanism of Action Nociceptin receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Insomnia
  • Phase I Interstitial cystitis; Overactive bladder
  • Preclinical Fibromyalgia
  • Discontinued Dental pain; Neuropathic pain

Most Recent Events

  • 15 Mar 2022 Phase-I clinical trials in Interstitial cystitis in USA (PO) (Imbrium Therapeutics pipeline, March 2022)
  • 15 Mar 2022 Phase-I clinical trials in Overactive bladder in USA (PO) (Imbrium Therapeutics pipeline, March 2022)
  • 06 Nov 2020 Imbrium Therapeutics completes a phase II trial in Insomnia in USA (PO) (NCT04035200)
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