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Delgocitinib - Japan Tobacco/LEO Pharma

Drug Profile

Delgocitinib - Japan Tobacco/LEO Pharma

Alternative Names: CORECTIM; JTE-052; JTE-052A; LEO 124249; LEO 124249 cream; LP-0133

Latest Information Update: 15 Mar 2024

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At a glance

  • Originator Japan Tobacco
  • Developer Japan Tobacco; LEO Pharma
  • Class Anti-inflammatories; Antiallergics; Antipsoriatics; Azetidines; Nitriles; Pyrimidines; Pyrrolidines; Skin disorder therapies; Small molecules; Spiro compounds
  • Mechanism of Action Janus kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Atopic dermatitis
  • Preregistration Eczema
  • Phase II Alopecia areata; Autoimmune disorders; Discoid lupus erythematosus; Hypersensitivity; Inverse psoriasis

Most Recent Events

  • 09 Mar 2024 Efficacy and adverse events data from a phase III OLE DELTA-3 trial in Eczema released by LEO Pharma
  • 24 Jan 2024 Efficacy and adverse events data from phase III DELTA FORCE trial for Eczema released by LEO Pharma
  • 05 Dec 2023 LEO Pharma completes a phase III trial for Eczema (Treatment-experienced) in Austria, Canada, France, Germany, Italy, Norway, Poland, Slovakia, Spain, and the UK (topical, Cream) (NCT05259722) (EudraCT2021-003543-16)
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