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Buprenorphine/naloxone - Indivior

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Drug Profile

Buprenorphine/naloxone - Indivior

Alternative Names: Buprenorphine hemiadipate HCl/naloxone HCl dihydrate; Buprenorphine hemiadipate hydrochloride/naloxone hydrochloride dihydrate; RBP-6300

Latest Information Update: 02 Oct 2021

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At a glance

  • Originator Reckitt Benckiser Pharmaceuticals
  • Developer Indivior
  • Class Antidotes; Benzofurans; Cyclopropanes; Drug withdrawal therapies; Isoquinolines; Morphinans; Opioid analgesics; Small molecules
  • Mechanism of Action Nociceptin receptor agonists; Opioid delta receptor antagonists; Opioid kappa receptor antagonists; Opioid mu receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Opioid-related disorders
  • New Molecular Entity No

Highest Development Phases

  • Discontinued Opioid-related disorders

Most Recent Events

  • 03 May 2016 Discontinued - Phase-I for Opioid abuse in United Kingdom (PO)
  • 03 May 2016 Discontinued - Phase-II for Opioid abuse (In volunteers) in United Kingdom (PO)
  • 03 May 2016 Discontinued - Phase-II for Opioid abuse in Sweden, Germany, Czech Republic, Austria (PO)

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