Drug Profile

PB 357

Alternative Names: PB-357

Latest Information Update: 28 Jan 2026

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At a glance

Originator Pfizer
Class Antineoplastics; Small molecules
Mechanism of Action Erb-b2 receptor tyrosine kinase antagonists; ERBB 4 receptor antagonists; ErbB receptor antagonists

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

28 Jan 2026 No recent reports of development identified for phase-I development in Cancer in USA (IV)
11 Jan 2024 Phase I development is ongoing USA
28 May 2022 No recent reports of development identified for phase-I development in Cancer in USA (IV)

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