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PDS 0301

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Drug Profile

PDS 0301

Alternative Names: M-9241; MSB0010360; NHS-huIL12; NHS-IL-12; NHS-IL12 human; NHS-IL12/MSB0010360; NHS-muIL12; PDS-01ADC; PDS-0301

Latest Information Update: 16 May 2024

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At a glance

  • Originator Merck Serono
  • Developer EMD Serono; Merck Serono; National Cancer Institute (USA)
  • Class Antineoplastics; Immunoconjugates; Immunotherapies; Interleukins; Recombinant fusion proteins
  • Mechanism of Action Immunostimulants; Interleukin 12 stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Cancer; Cholangiocarcinoma; Colorectal cancer
  • Phase I/II Prostate cancer
  • No development reported Solid tumours; Urogenital cancer

Most Recent Events

  • 16 May 2024 PDS Biotechnology plans a pivot trial in Squamous cell cancer (Late-stage disease) in 2024
  • 26 Oct 2023 National Cancer Institute (NCI) plans a phase II trial for Prostate cancer (Combination therapy, Second-line therapy or greater, Recurrent) in USA (SC, Injection) (NCT06096870)
  • 11 Oct 2023 Efficacy and adverse events data from a phase I/II trial in Prostate cancer released by PDS Biotech

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