Setmelanotide - Rhythm

Drug Profile

Setmelanotide - Rhythm

Alternative Names: BIM-22493; CAM 4072; RM-493

Latest Information Update: 21 Jun 2018

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At a glance

  • Originator Ipsen
  • Developer Charite - Universitatsmedizin Berlin; Ipsen; Rhythm
  • Class Amides; Antihyperglycaemics; Cyclic peptides; Cysteines; Disulfides; Obesity therapies
  • Mechanism of Action Melanocortin type 4 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Prader-Willi syndrome; Obesity
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Obesity
  • Phase I Diabetes mellitus

Most Recent Events

  • 18 Jun 2018 Rhythm plans to initiate a combined pivotal phase III trial for Bardet Biedl Syndrome and Alstrom Syndrome in the end of 2018
  • 18 Jun 2018 Efficacy data from a phase II trial in Obesity released by Rhythm
  • 14 Jun 2018 Rhythm Pharmaceuticals completes enrolment in its phase III trial for POMC deficient and leptin receptor (LepR) deficiency Obesity in USA (SC)
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