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Mirvetuximab soravtansine - ImmunoGen

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Drug Profile

Mirvetuximab soravtansine - ImmunoGen

Alternative Names: Anti-FOLR1-monoclonal-antibody-maytansinoid-conjugate-IMGN-853; ELAHERE; IMGN-853; M9346A-sSPDB-DM4; M9346A-sulfo-SPDB-DM4; MIRV; Mirvetuximab soravtansine-gynx; TAK-853

Latest Information Update: 31 Mar 2025

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At a glance

  • Originator ImmunoGen
  • Developer Hangzhou Zhongmei Huadong Pharmaceutical; ImmunoGen; Takeda
  • Class Antineoplastics; Drug conjugates; Immunotoxins; Maytansinoids; Monoclonal antibodies
  • Mechanism of Action Tubulin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Ovarian cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
  • Phase II Endometrial cancer; Triple negative breast cancer
  • Phase I/II Solid tumours

Most Recent Events

  • 25 Mar 2025 AbbVie plans a phase II trial for Ovarian cancer, Fallopian tube cancer and Peritoneal cancer (Late-stage disease) in July 2025 (NCT06890338)
  • 15 Mar 2025 Updated efficacy and adverse event data from the phase III MIRASOL trial in Ovarian, Peritoneal, and Fallopian tube cancer released by ImmunoGen
  • 12 Dec 2024 AbbVie completes the phase II PICCOLO trial in Ovarian, Peritoneal and Fallopian cancer (Monotherapy, Recurrent, Second-line therapy or greater) in the US, Australia, Belgium, Canada, France, Ireland, Italy, Spain and Germany (IV) (NCT05041257) (EudraCT-2021-003592-34)

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