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Alternative Names:
Anti-C5aR-215; IPH-5401; NN-8210; NNC-0215-0384
Latest Information Update: 12 Jul 2020
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At a glance
Originator
Novo Nordisk
Developer
Innate Pharma; MedImmune; Novo Nordisk
Class
Antineoplastics; Antirheumatics; Immunotherapies; Monoclonal antibodies
Mechanism of Action
Complement C5a receptor antagonists
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
No
New Molecular Entity
Yes
Highest Development Phases
Phase II
Pneumonia
Phase I
Liver cancer; Non-small cell lung cancer; Solid tumours
Discontinued
Rheumatoid arthritis
Most Recent Events
27 Apr 2020
Phase-II clinical trials in Pneumonia in France (IV) (NCT04371367) (EudraCT2020-001686-36)
07 Oct 2019
Innate Pharma plans a phase I/II trial for Solid tumours
01 Oct 2019
Preliminary efficacy, adverse events and pharmacodynamics data from the phase I STELLAR-001 trial in Solid tumours released by Innate Pharma
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