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Varisacumab - Affitech Research/International Biotech Center Generium/OncXerna Therapeutics

Drug Profile

Varisacumab - Affitech Research/International Biotech Center Generium/OncXerna Therapeutics

Alternative Names: Anti-VEGF antibody AT001/r84; Apagin; AT-001 - IBCG; AT001/r84; Bevacizumab biosimilar - International Biotech Center Generium; Fully humanised monoclonal antibody to VEGF; GNR-011; R-84

Latest Information Update: 02 Apr 2024

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At a glance

  • Originator Peregrine Pharmaceuticals; University of Texas Southwestern Medical Center
  • Developer Affitech Research AS
  • Class Antibodies; Antineoplastics; Eye disorder therapies; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Angiogenesis inhibitors; Vascular endothelial growth factor A inhibitors; Vascular endothelial growth factor receptor-2 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Discontinued Breast cancer; Colorectal cancer; Eye disorders; Glioblastoma; Non-small cell lung cancer

Most Recent Events

  • 27 Sep 2021 Discontinued - Phase-II/III for Breast cancer in Russia (IV)
  • 27 Sep 2021 Discontinued - Phase-II/III for Colorectal cancer in Russia (IV)
  • 27 Sep 2021 Discontinued - Phase-II/III for Eye disorders in Russia (IV)

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