Drug Profile


Alternative Names: AP-301

Latest Information Update: 15 Mar 2018

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At a glance

  • Originator APEPTICO Forschung und Entwicklung
  • Class Peptides
  • Mechanism of Action Inflammasome inhibitors; P38 mitogen-activated protein kinase inhibitors; Sodium channel agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Reperfusion injury; Acute lung injury; Pulmonary oedema; Pseudohypoaldosteronism
  • New Molecular Entity Yes
  • Available For Licensing Yes - Influenza virus infections

Highest Development Phases

  • Phase II Acute lung injury; Adult respiratory distress syndrome; Pulmonary oedema; Reperfusion injury
  • Preclinical Pseudohypoaldosteronism

Most Recent Events

  • 27 Feb 2018 Apeptico initiates enrolment in a phase II trial for Pulmonary oedema in patients with acute respiratory distress syndrome in Austria (EudraCT2017-003855-47)
  • 15 Dec 2016 Pharmacodynamics data from a preclinical trial in Pulmonary oedema released by Apeptico
  • 02 Dec 2016 Solnatide licensed to Apeptico in various European markets
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