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Simufilam - Cassava Sciences

Drug Profile

Simufilam - Cassava Sciences

Alternative Names: C0105; C0105M; Filora; PTI-125; PTI-910; Simufilam hydrochloride; Sumifilam - Cassava Sciences

Latest Information Update: 12 Feb 2024

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At a glance

  • Originator Pain Therapeutics
  • Developer Cassava Sciences
  • Class Antidementias; Small molecules
  • Mechanism of Action Microfilament protein modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Alzheimer's disease

Most Recent Events

  • 07 Feb 2024 Topline adverse events and efficacy data from the phase II trial in Alzheimer's disease released by Cassava Sciences
  • 08 Jan 2024 Cassava Sciences plans a phase I pharmacokinetics trial for Alzheimer's disease (In volunteers) in February 2024 (PO) (NCT06195319)
  • 10 Nov 2023 Cassava Sciences completes enrolment in the phase III clinical trial in Alzheimer's disease in USA, Canada, South Korea, and Puerto Rico (PO) (NCT05026177)
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