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Simufilam - Cassava Sciences

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Drug Profile

Simufilam - Cassava Sciences

Alternative Names: C0105; C0105M; Filora; PTI-125; PTI-910; Simufilam hydrochloride; Sumifilam - Cassava Sciences

Latest Information Update: 27 Dec 2024

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At a glance

  • Originator Pain Therapeutics
  • Developer Cassava Sciences
  • Class Antidementias; Ketones; Small molecules
  • Mechanism of Action Microfilament protein modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Alzheimer's disease

Most Recent Events

  • 09 Dec 2024 Cassava Sciences re initiates phase III PTI-125-10 trial in Alzheimer's disease (In adults, In the elderly) in Canada, Puerto Rico, Australia, South Korea and USA (PO) (NCT05575076)
  • 25 Nov 2024 Cassava Sciences terminates phase III PTI-125-10 trial in Alzheimer's disease (In adults, In the elderly) in Canada, Puerto Rico and USA (PO) (NCT05575076)
  • 25 Nov 2024 Cassava Sciences terminates phase III REFOCUS-ALZ trial in Alzheimer's disease in the US, Canada, South Korea and Puerto Rico (PO) (NCT05026177)

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