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SAR 405838

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Drug Profile

SAR 405838

Alternative Names: MI-773; SAR-405838

Latest Information Update: 24 Oct 2021

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At a glance

  • Originator University of Michigan
  • Developer Sanofi
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Proto-oncogene protein c-mdm2 inhibitors; Tumour suppressor protein p53 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Lymphoma; Solid tumours

Most Recent Events

  • 05 Mar 2018 Sanofi completes a phase I trial in Solid-tumours and Lymphoma in France, Netherlands, USA (NCT01636479)
  • 18 May 2016 Chemical structure information added
  • 31 May 2015 Discontinued - Phase-I for Lymphoma and Solid tumours in Netherlands (PO)

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