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Research programme: oncolytic viruses - Transgene

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Drug Profile

Research programme: oncolytic viruses - Transgene

Alternative Names: anti-PD-1 immune checkpoint inhibitor - Transgene; J43-armed-Western Reserve oncolytic vaccinia virus

Latest Information Update: 28 Oct 2022

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At a glance

  • Originator Transgene
  • Class Antibodies; Antineoplastics; Gene therapies; Immunotherapies; Oncolytic viruses
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Cell death stimulants; Gene transference; Immunologic cytotoxicity; Programmed cell death 1 receptor antagonists; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • No development reported Solid tumours

Most Recent Events

  • 28 Oct 2022 No recent reports of development identified for preclinical development in Solid-tumours in France (IV)
  • 18 Jan 2022 Transgene and PersonGen entered into collaboration to evaluate a new combination therapy against Solid tumours
  • 09 Jun 2021 Transgene has patent protection for oncolytic virus (OV) backbone VVcopTK-RR- in Japan

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