Alteplase - Boehringer Ingelheim

Drug Profile

Alteplase - Boehringer Ingelheim

Alternative Names: Actilyse; Activacin; Activase; Cathflo; G-11021; G-11035; G-11044; GMK-527; GRTPA; IV rt-PA; Recombinant tissue plasminogen activator - Boehringer; RG-3626; rt-PA - Boehringer; rTPA - Boehringer; t-PA - Boehringer; Tissue plasminogen activator - Boehringer; Tissue type plasminogen activator - Boehringer

Latest Information Update: 24 Mar 2018

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At a glance

  • Originator Boehringer Ingelheim
  • Developer Boehringer Ingelheim; Genentech; Washington University School of Medicine
  • Class Plasminogen activator enzymes; Recombinant proteins; Thrombolytics
  • Mechanism of Action Plasminogen activators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Catheter thrombosis; Myocardial infarction; Pulmonary embolism; Stroke
  • Phase III Deep vein thrombosis

Most Recent Events

  • 11 Dec 2017 Boehringer Ingelheim completes a phase III trial for Stroke in China (IV) (NCT02930837)
  • 01 Jan 2017 Genentech completes the phase III ATTRACT trial in Deep vein thrombosis (In adolescents, In adults, In the elderly) in USA (IV) (NCT00790335)
  • 21 Dec 2016 Genentech terminates the phase IIIb PRISMS trial for Stroke in USA (IV) (NCT02072226)
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