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Abacavir/lamivudine/lopinavir/ritonavir - Cipla/Drugs for Neglected Diseases Initiative

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Drug Profile

Abacavir/lamivudine/lopinavir/ritonavir - Cipla/Drugs for Neglected Diseases Initiative

Alternative Names: 4-in-1 fixed combination ARV therapy - Cipla/Drugs for Neglected Diseases Initiative Foundation; 4-in-1 paediatric antiretroviral drug combination - Cipla/Drugs for Neglected Diseases Initiative Foundation; Abacavir/lamivudine/lopinavir/ritonavir; Lopinavir/r/lamivudine/abacavir; Lopinavir/ritonavir/3TC/ABC; Lopinavir/ritonavir/3TC/AZT; Lopinavir/ritonavir/lamivudine/abacavir; Lopinavir/ritonavir/lamivudine/zidovudine; LPV/r/ABC/3TC - Cipla/Drugs for Neglected Diseases Initiative Foundation; LPV/r/AZT/3TC - Cipla/Drugs for Neglected Diseases Initiative Foundation; Quadruple fixed combination HIV therapy - Cipla/Drugs for Neglected Diseases Initiative Foundation

Latest Information Update: 16 Oct 2025

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At a glance

  • Originator Cipla
  • Class Amides; Antiretrovirals; Carbamates; Cyclopentanes; Cyclopropanes; Dideoxynucleosides; Pyrimidine nucleosides; Pyrimidinones; Small molecules; Thiazoles
  • Mechanism of Action HIV protease inhibitors; HIV replication inhibitors; Nucleoside reverse transcriptase inhibitors; PRINS expression inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II HIV infections

Most Recent Events

  • 16 Oct 2025 Pharmacokinetics data from a phase I/II trial in HIV infections presented at the 32th Conference on Retroviruses and Opportunistic Infections (CROI-2025)
  • 03 Mar 2024 Pharmacokinetics data from a phase I/II trial in HIV infections presented at the 31th Conference on Retroviruses and Opportunistic Infections (CROI-2024)
  • 19 Feb 2023 Pharmacokinetics and adverse events data from a phase I/II trial in HIV infections presented at the 30th Conference on Retroviruses and Opportunistic Infections (CROI-2023)

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