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Tarloxotinib - Rain Oncology/University of Auckland

Drug Profile

Tarloxotinib - Rain Oncology/University of Auckland

Alternative Names: Hypoxin™; PR 610; Tarlox; Tarloxotinib bromide; TH-4000

Latest Information Update: 11 Mar 2024

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At a glance

  • Originator University of Auckland
  • Developer Proacta; Rain Oncology; Threshold Pharmaceuticals
  • Class Aniline compounds; Antineoplastics; Imidazoles; Pyridines; Pyridones
  • Mechanism of Action Epidermal growth factor receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Non-small cell lung cancer
  • Discontinued Solid tumours; Squamous cell cancer

Most Recent Events

  • 31 Dec 2023 Rain Oncology terminates a phase I/II clinical trials in Non-small cell lung cancer (Combination therapy, Second-line therapy or greater, Metastatic disease) in USA (IV) due to business reasons (NCT05313009)
  • 14 Mar 2022 University of Auckland plans a phase I trial for Head and neck cancer (Late-stage disease, First-line therapy) in Australia and New Zealand (ACTRN12622000369729)
  • 07 Mar 2022 Phase-I/II clinical trials in Non-small cell lung cancer (Combination therapy, Second-line therapy or greater, Metastatic disease) in USA (IV) (NCT05313009)

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