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Brivoligide - Adynxx

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Drug Profile

Brivoligide - Adynxx

Alternative Names: AYX-1; Brivoligide-sodium

Latest Information Update: 20 Jul 2020

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At a glance

  • Originator Adynxx
  • Class Analgesics; Oligonucleotides
  • Mechanism of Action Early growth response protein 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Pain; Postoperative pain

Most Recent Events

  • 09 Jul 2020 Adynxx withdraws a phase II ADYX-005 trial for Postoperative pain in patients undergoing unilateral total knee arthroplasty or TKA prior to enrolment owing to delay in trial initiation due to COVID-19 pandemic in USA (NCT03797612)
  • 09 Jul 2020 Adynxx withdraws a phase II ADYX-006 trial for Postoperative pain in patients undergoing mastectomy with immediate tissue expander or implant placement prior to enrolment owing to delay in trial initiation due to COVID-19 pandemic in USA (NCT04104919)
  • 14 Nov 2019 Adynxx plans the phase II ADYX-005 trial for Postoperative pain in USA in participants undergoing unilateral total knee arthroplasty or TKA in the first quarter of 2020 (NCT03797612)

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