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Brivoligide - Adynxx

Drug Profile

Brivoligide - Adynxx

Alternative Names: AYX-1; Brivoligide-sodium

Latest Information Update: 20 Dec 2018

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At a glance

  • Originator Adynxx
  • Class Analgesics; Oligonucleotides
  • Mechanism of Action Early growth response protein 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Pain; Postoperative pain

Most Recent Events

  • 22 Apr 2019 Adynxx plans the phase II ADYX-006 trial for Postoperative pain (In patients undergoing mastectomy with immediate tissue expander or implant placement) in 2019
  • 23 Jan 2019 Adynxx plans the phase II ADYX-005 trial for Postoperative pain in USA in participants undergoing unilateral total knee arthroplasty or TKA in May 2019 (NCT03797612)
  • 13 Dec 2018 Adynxx receives Notice of Award from the National Institute on Drug Abuse National Institutes of Health for clinical development brivoligide for postoperative pain
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