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Brontictuzumab

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Drug Profile

Brontictuzumab

Alternative Names: Anti-Notch 1; Anti-Notch 1 monoclonal antibody; OMP-52M51

Latest Information Update: 02 Jul 2023

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At a glance

  • Originator OncoMed Pharmaceuticals
  • Developer OncoMed Pharmaceuticals; University of Texas M. D. Anderson Cancer Center
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Immunomodulators; Notch-1 receptor antagonists; Stem cell inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Adenoid cystic carcinoma; Colorectal cancer; Solid tumours
  • Discontinued Haematological malignancies

Most Recent Events

  • 28 Feb 2020 No recent reports of development identified for phase-I development in Colorectal-cancer(Combination therapy, Metastatic disease, Second-line therapy or greater) in USA (IV)
  • 24 Apr 2019 OncoMed Pharmaceuticals has been acquired by Mereo BioPharma
  • 28 Jan 2019 No recent reports of development identified for clinical-Phase-Unknown development in Adenoid-cystic-carcinoma in USA (IV)

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